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Menarini Stories

Familial Hypercholesterolaemia Awareness Day: addressing the global clinical gap
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September 24: bringing attention to on an inherited metabolic disorder

September 24 marks the global Familial Hypercholesterolaemia (FH) Awareness Day,¹ a critical initiative dedicated to raising awareness of a genetic disorder that remains frequently underdiagnosed in routine clinical practice. Characterised by a lifelong elevation of low-density lipoprotein cholesterol(bad cholesterol) present from birth, FH carries a heightened risk of myocardial infarction, coronary heart disease and sudden cardiac death, driven by this chronic hypercholesterolaemia.²,³

The Silent Epidemic: Underdiagnosed and Undertreated

Diagnosing FH remains a considerable challenge.4 Despite affecting approximately 1 in 200 to 250 individuals3. Translating to roughly 2 million adults and 500,000 children in Europe; only about 5% of these children are diagnosed in time.

The median age for diagnosis is 44 years and only 2% of the adults are diagnosed before the age of 18 years, when atherosclerotic cardiovascular disease has already been developed.²,⁴

Crucially, diagnosis is only half the battle: real world registries has shown fewer than 3% of patients currently achieve their recommended LDL-C target values.⁴ Because FH progresses without symptoms, this lifelong exposure silently drives premature heart disease if left untreated.⁴

Turning the tide: how readily FH can be identified

The reassuring reality is that FH can be identified through a simple blood test, combined with an evaluation of family history, and confirmed through genetic testing.5

Clinicians should be alert to the two principal clinical indicators of FH6:

  • Elevated LDL-C levels that do not respond to diet and exercise alone.
  • A family history of premature heart disease or early heart attacks.

Menarini Group’s commitment to cardiovascular health

At Menarini Group cardiovascular health is at the heart of what we do. Awareness days are a vital reminder of how early risk detection can rewrite the story for patients and their families.

This FH Awareness Day, we encourage everyone to look into their family health history. Talk to your doctor, check your cholesterol levels, and help raise awareness to ensure earlier diagnosis for this silent genetic condition.

IM-08-2026

Sources:

1. Family Heart Foundation. FH awareness day. Available at: https://familyheart.org/fh-awareness-day - Last accessed June 2026. 2. Albert W, et al. European Heart Journal, 2026; ehag382 

3. Kalia I, et al. J Clin Transl Sci. 2023 Apr 5;7(1):e92.

4. Arnold N, Koenig W. Rev Cardiovasc Med. 2023 Aug 17;24(8):236. 5. Family Heart Foundation. Familial Hypercholesterolemia. Available at: https://familyheart.org/familial-hypercholesterolemia — Last accessed June 2026.

6. Family Heart Foundation. Diagnosing Familial Hypercholesterolemia. Available at: https://familyheart.org/diagnosing-familial-hypercholesterolemia — Last accessed June 2026.

Fraud Warning Disclaimer

Please be aware that certain individuals might approach you by falsely presenting themselves as our employees, affiliates, agents or representatives. Under this false pretense, they might try to gain access to your personal information or to acquire money or other valuables from you by offering fictitious employment opportunities or by claiming that they are contacting you on our behalf. The contacting individual or organisation may, for example, claim that we can guarantee your employment if you pay them a certain amount of money. Such fraudulent offers and claims are usually received via email, the internet, text message, phone, etc. These claims and offers are fraudulent and invalid and you are strongly advised to exercise great caution when you receive such an offer of employment or notice. Be very mindful of such scams.Below we list some of the features such an offer or claim may have:

Below we list some of the features such an offer or claim may have:

• It may propose a phone or instant message program interview and/or money as a precondition for hiring You may be requested to disclose private, sensitive or confidential information

• You may be told that you were contacted in such a manner because it is a matter of urgency

Such an offer or claim will probably be in the form of an email sent from a fake email address or from a free email address and not from an official Menarini Group email address. Please take extra caution while examining such an email address, as the perpetrators may misspell an official Menarini Group email address and use a slightly modified version of an official Menarini Group email address.

Please note that you will never receive a fraudulent employment offer or any other similar claim from us, because we do not provide any recruitment services. Moreover, we will never ask you for money in exchange for employment opportunities or other similar services. Any such offer of employment or any other service in exchange for fees that claims to be from us is deceitful and part of a fraud.

Criminal and/or civil liabilities may arise from such actions and we intend to cooperate with competent law enforcement agencies. Accordingly, we would ask you to immediately get in touch with us upon receiving a suspicious offer or claim and additionally notify the police or other competent authority.

In any case, please disregard any written or oral request related to a job offer or an interview that you believe is or might be fraudulent or suspicious.

Please note that under no circumstances shall Menarini Group be held liable or responsible for any claims, losses, damages, expenses or other inconvenience resulting from or in any way connected to the actions of these imposters.

Fake Job Awareness

Fake job advertisements are increasingly appearing on the internet and social media. Please be aware of employment scams where people or entities misuse Menarini or Stemline's names to post fake job advertisements.

Stemline will only extend an offer with an interview process and will never charge any money for joining our company. All our current job openings are displayed on the Careers section of our Menarini website, accessible here: https://www.menarini.com/en-us/careers/careers-in-oncology

How to protect against a fake job scam:

  • Never pay for anything in response to a job application or offer.
  • If you receive an offer for a job, you did not apply for, it is fake.
  • A job offer without a personal interview or interaction is a scam.
  • Menarini or Stemline never post jobs on Facebook; if you see one, it is a scam.
  • Watch out for badly written emails or emails not coming from an official Menarini or Stemline company domain.
  • Always check the official company Menarini-Stemline website to ensure that the job exists.
  • Listen to your instincts; if you suspect a scam, it probably is.