Pharmaceuticals

Cardiometabolic

Cardiology

Cardiovascular diseases represent the main commitment of Menarini thanks to the company’s experience of more than 30 years in making innovative cardiovascular drugs available for the patients. Menarini is focused on treating the most widespread diseases of the cardiovascular area and on the prevention and reduction of risk factors associated with chronic conditions like hypertension and angina with the commitment to help patients in restoring their quality of life. Basing on the company’s vision, Menarini has focused its energy also on the research to optimise existing therapeutic tools and on creating new, innovative drugs and therapeutic aids.

chronic stable angina

Chronic stable angina

Chronic stable angina is the main manifestation of stable coronary artery disease and arises from a mismatch between myocardial oxygen supply and demand...

READ MORE

heart failure

Heart failure

Heart failure is considered as the whole set of signs and symptoms developed when the heart loses its ability to pump blood around the body efficiently...

READ MORE

hypertension

Hypertension

Before speaking about hypertension, we should know that our blood pressure is recorded by two numbers: the systolic blood pressure (SBP), higher number...

READ MORE

myocardial infarction

Myocardial infarction

Myocardial infarction is a serious medical emergency in which the supply of blood to the heart is suddenly blocked, usually by a blood clot. It is considered...

READ MORE


Diabetes

Diabetes mellitus occurs when the pancreas is no longer able to produce enough insulin, or when the body cannot make good use of it. Not being able to produce insulin or use it effectively causes elevated glucose levels in the blood, that can lead to serious health problems.

Chronic diabetes conditions include type 1 and type 2 diabetes:

  • Type 1 diabetes can develop at any age, though it often appears during childhood or adolescence. In the case of type 1 diabetes the body produces very little or no insulin, which means that daily insulin injections are needed to keep blood glucose levels under control.
  • Type 2 diabetes is more common in adults and accounts for around 90% of all diabetes cases. Type 2 diabetes occurs when the body does not make good use of the insulin that it produces. The cornerstone of type 2 diabetes treatment is a healthy lifestyle, including increased physical activity and a healthy diet. However, over time, most people with type 2 diabetes require anti-diabetic pharmacological treatment to keep their blood glucose levels under control.

Potentially reversible diabetes conditions include prediabetes — when blood sugar levels are higher than normal, but not high enough to be classified as diabetes — and gestational diabetes, which may occur during pregnancy and generally resolves after the baby is delivered.

Diabetes symptoms vary depending on how high blood sugar levels become. Some people, especially those with pre-diabetes or type 2 diabetes, may not experience symptoms initially. In type 1 diabetes, symptoms tend to come on quickly and be more severe.

Some of the signs and symptoms of type 1 and type 2 diabetes are: frequent urination, increased thirst, extreme hunger, frequent infections, slow-healing sores, blurred vision, fatigue and irritability.

The goals in diabetes mellitus treatment are to eliminate symptoms and to prevent, or at least slow, the development of harmful complications in different organs, such as kidneys and eyes, as well as in nervous and cardiovascular systems.

Menarini’s presence in diabetes care has a long history through well-known and long-established products. In addition Menarini is constantly and strongly committed to expanding this therapeutic area by evaluating new innovative opportunities with the aim of taking better care of diabetic patients.


Gout

Diet (red meat, seafood), genetic factors, male gender, increased age ,overweight, menopause, alcohol, myeloproliferative malignancies, renal impairment, dehydration and medicines (diuretics, some hypertensive drugs and anti-neoplastic drugs) are mostly associated to gout.

The clinical progression of gout can be defined by four stages:

  • Asymptomatic hyperuricemia
  • Acute gout or gout flare: characterized by the deposition of crystals intra joint causing inflammation. It is associated to intense pain, redness, heat and swelling at the affected joint and surrounding tissues, such as big toe and elbow. Most frequently the attacks occur during the night waking up the patient. Different factors like food, stress, drugs and alcohol can trigger the attacks. Usually the symptoms disappear in 1–2 weeks. With the progression of the disease, the frequency of the episodes increases as the number of joints involved and the interval between every episodes is every time shorter.
  • Intercritical period: phase between two acute gout episodes without any signs or symptoms. It can be prolonged by avoiding the triggering factors.
  • Chronic gout: it occurs when none therapy has been established, usually after some years from the first acute episode. Its distinctive feature are the thopi, large visible bumps made of urate crystals. If not treated it can lead to joint deformity, osteoarthritis and bone loss, urate nephropathy and ocular complications. It is important to underline that chronic hyperuricemia is a risk factor for cardiovascular disease.

Gout is a treatable disease. The purpose of the therapy is to promote the dissolution of the crystal deposits and getting the blood uric acid level under control in order to reduce the formation of new crystals. Dietary modifications, reduction of alcohol consumption and weight loss are key points for the correct management of gout. In case of acute attacks NSAIDs are usually effective. Your doctors may prescribe your different types of drugs to treat this condition.

Pharmaceuticals

Innovation & Research

We are highly committed to developing effective solutions to address the global threat associated with antimicrobial resistance. Discover more about our R&D projects in the anti-infectives area.

Read More