Partnering

Our recent agreements

Oncology

In February 2025 Tempus Al, Inc. (NASDAQ: TEM), a technology company leading the adoption of Al to advance precision medicine and patient care, and the Menarini Group, and Stemline Therapeutics, Inc., announced a new collaboration.
The two companies will leverage Next – Tempus’ Al-enabled care pathway intelligence platform to support patients with HR+ HER2- metastatic breast cancer by helping clinicians to determine when an ESR1 test may be appropriate.

In December 2024 Menarini Group and lnsilico Medicine, a clinical stage generative artificial intelligence (Al)-driven biotechnology company, have entered into a second exclusive licensing collaboration granting Menarini Group global rights to develop and commercialize a preclinical small molecule targeting high unmet need in oncology.

 

In December 2023 Menarini Group and lnsilico Medicine, a clinical stage generative artificial intelligence (Al)-driven biotechnology company, have entered into an exclusive licensing collaboration granting Menarini Group global rights to develop and commercialize a preclinical small molecule KAT6 protein inhibitor targeting hormone sensitive cancers and other oncology indications. In 2024 the asset entered in clinical development.

In December 2021 Menarini Group was granted exclusive commercialization rights for NEXPOVIO (selinexor) in Europe, Latin America, and the CIS countries. Selinexor is a first-in-class oral Selective Inhibitor of Nuclear Export (XPO1) and currently approved in the US for multiple myeloma and diffuse large B-cell lymphoma. Selinexor was also granted the marketing authorisation in EMA, UK and other countries in multiple myeloma. Selinexor is being developed for the treatment of additional hematologic and solid tumor indications.

In July 2020 Menarini Group obtained global development and commercialization rights for elacestrant (ORSERDU), a first-in-class oral Selective Estrogen Receptor Degrader (SERD). Elacestrant is currently approved by FDA, EMA and in other countries for the treatment of postmenopausal women and men with advanced ER+/HER2- breast cancer and in clinical development in additional indications.

Cardiometabolic

NewAmsterdam Pharma and the Menarini Group Sign Licensing Deal to Commercialize Obicetrapib in Europe

June 28, 2022 - Exclusive licensing deal between NewAmsterdam Pharma and the Menarini Group to commercialize obicetrapib in Europe. Obicetrapib is a next-generation oral, low-dose and once-daily cholesteryl ester transfer protein (CETP) inhibitor therapeutic candidate, currently in multiple, global phase 3 development for LDL-lowering and cardiovascular events prevention as adjunct treatment  in patients with dyslipidemia despite maximally tolerated statin therapy. The collaboration expands Menarini's existing cardiology portfolio of 18 products, which address the most widespread cardiometabolic diseases and aim to prevent and reduce risk factors associated with chronic conditions. Obicetrapib, if approved, could radically alter the treatment landscape in cardiovascular disease by providing an effective and oral option for hyperlipidemia patients in Europe.

Respiratory

Menarini strengthened its respiratory value proposition with various commercial deals in Asthma and COPD for GSK’s Ellipta’s Portfolio (LABA, LAMA, LAMA/LABA). In addition, Nucala® (mepolizumab) is also included for severe Asthma

Anti-Infectives

Melinta and Menarini have entered into a commercial and co-development agreement for Quofenix®, Vaborem™, Orbactiv® and Minocin® in 68 countries, thus building a high value antinfectives platform.

Venatorx Pharmaceuticals and Menarini Group entered into a commercial agreement for Cefepime-Taniborbactam in 96 countries. Cefepime-taniborbactam is an investigational intravenous (IV) beta-lactam/beta-lactamase inhibitor (BL/BLI) antibiotic combination being developed for the treatment of complicated urinary tract infections (cUTIs), and hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP).