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PRACINOSTAT

Inhibitor of class I, II, and IV HDAC

ONCOLOGY

CURRENT DEVELOPMENT PHASE: myelodysplastic syndrome

preclinicl
phase i
phase ii
phase iii
pre-registration
post-registration

PRACINOSTAT (MDS)

In December 2018, the Menarini Group signed with Helsinn an exclusive licensing agreement to commercialize Pracinostat worldwide (excluding US, Canada, Japan and South America).

Pracinostat is an inhibitor of class I, II, and IV histone deacetylase, currently in clinical development for the treatment of naïve patients with higher risk myelodysplastic syndrome (MDS), in an open label phase II study in combination with Azacitidine.

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