Our site uses cookies to offer a better navigation functionality, including "third party" cookies and "profiling cookies" designed to send on-line commercial communications in line with the preferences expressed by the user while surfing the internet. Should you wish to receive more information, or deny your consent to some or all cookies, click here to disable them. Upon proceeding with browsing this website, you will be consenting to the use of cookies.

Biotechnology

Cutting-edge technologies: Menarini Biotech
Biotechnology was born with the discovery of the DNA double helix in the 50s: on April 25, 1953 the first article was published in Nature by James Watson and Francis Crick describing this structure.
Giant steps have led to the development of organic products in less than half a century. Menarini Biotech represents industry excellence.

Why biotechnology?
The creation of a drug using a biotechnological approach has a number of advantages compared to the use of synthetic molecules.
Biotechnology provides the ability to produce drugs that are best suited to the physiology of man and therefore are extremely selective because they aim at a precise target, thereby reducing the drug’s side effects and increasing the therapy’s effectiveness.
The goal of biotechnology is to produce drugs by using living organisms such as bacterial cells, yeast, mammalian cells, etc., that are placed in culture to produce substances with pharmacological activity, such as monoclonal antibodies for the treatment of tumors.

New discoveries, new possibilities, new treatments on the horizon.
Biotechnology is the ideal remedy for curing certain diseases and the right solution for creating certain types of drugs: biological molecules are sometimes the only solution when drugs cannot be manufactured synthetically.
Biotechnology is the last frontier of research and the new foundation of medicine: biological drugs allow science to do what the synthetic drugs still cannot do, and for this reason Menarini Biotech invests in research and innovation.

 

PILOT AND INDUSTRIAL PLANTS

Menarini Biotech has the following ‘state of the art’ manufacturing and development facilities together with cutting edge analytical and protein charaterisation laboratories.
These are staffed with noted international experts in their fields fully committed to enhancing Pomezia as a biotechnology centre of excellence.

Cultivation

  • Mammalian cells (somatic/hybridoma cells)

    • Microbioreactors
    • Pilot scale 5-15 litres (stirred tanks, perfusion, hollow fibre, single use systems)
    • Industrial scale 300-1500 litres (stirred tanks)

  • Micro-organisms

    • Pilot scale 2-10 litres
    • Industrial scale 300 litres
Downstream 
  • Homogenisation
  • CChromatography (capacity up to 2000 l/h with appropriate column sizes)
  • Micro-and ultra-filtration
  • Nanofiltration
Clean Rooms
  • Cultivation Class D
  • Downstream Class C
FROM THE LAB TO INDUSTRIAL SCALE

  • Molecular biology
  • Cell engineering
  • Fermentation and downstream technologies
  • Development and validation of bio-process with genetically-modified organisms
  • State of the art characterisation of recombinant proteins
  • Excellent Quality Control
  • Full Quality Assurance
  • Italian Ministry of Health Approved for clinical phase drugs for human use

Therapeutic Areas

 

Discover all of Menarini's products marketed in Italy.

READ MORE »

Diagnostics

 

Advanced Technology

READ MORE »

The Menarini Group

 

Discover the leading Italian pharmaceutical company in the world.

READ MORE »

Quality first

 
 

Quality: point of departure and arrival for our drugs.

READ MORE »